HER2 PV Pregnancy Program
If you are pregnant or plan to become pregnant, Phesgo may be harmful to an unborn baby. If there is a need for Phesgo treatment when you are pregnant, your doctor will discuss the risks and benefits to you and the unborn baby. You should use effective contraception to avoid becoming pregnant while you are being treated with Phesgo and for 7 months after stopping treatment.
If you become pregnant while receiving Phesgo, or within 7 months following the last dose of Phesgo, please contact your oncologist for medical advice. Report the pregnancy to Roche Patient Safety at nz.drugsafety@roche.com or 0800 276 243.
Additional information will be requested during a Phesgo-exposed pregnancy and the first year of the infant’s life. This will enable Roche to better understand the safety of Phesgo and to provide appropriate information to health authorities, healthcare providers, and patients.
For additional information, please refer to the Phesgo Consumer Medicine Information at www.medsafe.govt.nz
Phesgo® Phesgo® (pertuzumab and trastuzumab) 600 mg/600 mg and 1200 mg/600 mg solution for subcutaneous injection is a Prescription Medicine used for early breast cancer, either before or after surgery and for breast cancer that has spread to other parts of the body.
Ask your doctor if Phesgo is right for you.
Phesgo is a funded medicine for metastatic breast cancer for patients who meet defined criteria from 1 December 2025. A prescription charge and doctor’s fees apply.
Phesgo is an unfunded medicine for neoadjuvant or adjuvant treatment of early breast cancer. Ask your health professional about the cost of the medicine and other fees that may apply.
Use only as directed. If symptoms continue or you have side effects, see your healthcare professional. For more information about Phesgo:
● talk to your health professional; or
● visit medsafe.govt.nz for Phesgo Consumer Medicine Information; or
● visit cancertreatments.co.nz or call Roche on 0800 276 243.
Phesgo has risks and benefits.Possible less serious side effects include: constipation, indigestion or stomach pain, sore mouth, throat or gut, fatigue or tiredness, getting tired more easily after light physical activity such as walking, shortness of breath especially when lying down or being woken from your sleep with shortness of breath, nail problems especially inflammation where the nail meets the skin, hair loss, feeling dizzy, tired, looking pale, hot flushes, frequent infections such as fever, severe chills, sore throat or mouth ulcers, nose bleeds, heartburn, eye problems such as producing more tears, insomnia (trouble sleeping), weak, numb, tingling, prickling or painful sensations mainly affecting the feet and legs, dry, itchy or acne like skin, loss of appetite, loss of or altered taste, joint or muscle pain, muscle
weakness, sore throat, red, sore or runny nose, flu-like symptoms, and fever which may lead to infection of the ear, nose, or throat, pain at the injection site, reddened skin (erythema) and bruising at the injection site, general pain in the body, arms, legs and/or belly including sharp jabbing, throbbing, freezing or burning pain, feeling pain from something which should not be painful, such as a light touch, reduced ability to feel changes in temperature, loss of balance or coordination.
Do not use Phesgo if: you are pregnant or if you are allergic to pertuzumab, trastuzumab, or any of the ingredients in Phesgo.
Tell your doctor if: you have a history of heart problems such as heart failure, abnormal beating of the heart, poorly controlled blood pressure or have had a recent heart attack, you have previously been treated with chemotherapy medicines known as anthracyclines (e.g. doxorubicin) or radiation therapy (these medicines or treatment can damage heart muscle and increase the risk of heart problems with Phesgo), you take any medicines for any other condition, you are allergic to any other medicines or any other substances such as foods, preservatives or dyes.
Tell your doctor immediately or go to your nearest Accident and Emergency Centre if you notice any of the following signs and symptoms: allergic or anaphylactic reactions: including swelling of your face, lips, tongue or throat with difficulty breathing, or swelling of other parts of your body, shortness of breath, wheezing or trouble breathing, rash, itching or hives on the skin, feeling sick (nausea), fever or chills, headache or feeling tired; injection related reactions: these may be mild or more severe and may include feeling sick or vomiting, fever, chills, feeling tired, headache, loss of appetite, joint and muscle pains and hot flushes; heart problems: slower or faster heartbeat than usual, fluttering of the heart, abnormal or irregular heartbeat, cough, shortness of breath, swelling (fluid retention) in your legs or arms; tumour lysis syndrome (where cancer cells die quickly): kidney problems – signs include weakness, shortness of breath, fatigue and confusion, heart problems – signs include fluttering of the heart or a faster or slower heartbeat, seizures (fits), vomiting or diarrhoea and tingling in the mouth, hands or feet; severe chest pain: spreading out to the arms, neck, shoulder or back and diarrhoea: may be mild or moderate.
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